Oral Fluid Drug Screen Device

What is the oral fluid drug test?

As an alternative to urine drug testing, saliva drug testing or oral fluid drug testing is also used to assess drug use habits. Oral fluid (saliva) is one of the fastest-growing matrices used in drug abuse testing and is part of Thermo Scientific™’s extensive menu for drug abuse testing. Oral fluid is the fluid found in the oral cavity (mouth), consisting of saliva from the salivary glands, cells and tissues of the gum and cheek, cellular debris, microorganisms, and food residues.

Oral fluid drug screen device is made up mostly of water, but it also contains electrolytes and enzymes. Due to passive diffusion from blood to saliva, drugs can be detected in oral fluid shortly after administration and absorbed into the blood. That is why oral fluids detect recent drug use. Oral fluids can be used as an alternative or adjunct to urine drug tests.

Collection of oral fluids reduces the risk of sample adulteration

One of the biggest concerns with urine testing can be an adulteration of the sample, leading to a false negative result. For urine tests, patients must report to a collection station for supervised sample collection. Alternatively, oral fluids are collected in an open environment, anytime, anywhere. Sample collection is easy and only takes 10 minutes from start to finish.

A collection device containing an absorbent pad is placed in the participant’s mouth and some devices, such as the Oral-Eze™ oral fluid collection system, have a colored indicator to indicate when there is enough oral fluid in the pad. The pad is then placed in a buffer and sent to the laboratory for analysis. The entire collection process typically takes less than 10 minutes. Since privacy is not an issue, collection can be done on-site (anywhere, anytime), making sample collection be more convenient.

Automation vs. Point-of-Care Testing

Laboratories receive numerous samples of both urine and oral fluids. Depending on the number of samples, automated analysis can be easier and cheaper compared to point-of-care (POC) testing. Today, the POC oral fluids test is used primarily in the field to detect driving under the influence. These tests use lateral flow and are read visually. Although they are improving, POC assays are generally considered less accurate and less precise than automated tests.

  • Use existing collection sites and shipping methods with the Oral-Eze Collection System
  • Provides the option to collect on-site for unscheduled testing, such as random screening at the workplace
  • Greatly reduces sample adulteration because the collection is observed from start to finish
  • Drugs are stable in the Oral-Eze collection device for up to 21 days at 2-30oC

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